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Updated: Jan 14, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
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Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

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在RNA-蛋白相互作用的结合部位外的indel多态的结构效应是由选择形成的选择

Carlos Owusu-Ansah1, Elan Shatoff2,3, Ralf Bundschuh1,2,3,4,5

  • 1Interdisciplinary Biophysics Graduate Program, The Ohio State University, Columbus, Ohio, United States of America.

PLoS computational biology
|October 21, 2025
PubMed
概括

称为indels的基因组变异可以通过改变蛋白质结合部位之外的RNA结构来改变基因调节. 净化选择有利于自然的内接,导致较小的结合变化,特别是在HuR结合部位附近.

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