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相关概念视频

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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相关实验视频

Updated: Jan 14, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
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MouseOmics:用于小鼠生物研究的多omics数据库.

Xin Tian1, Yifan Teng2, Miaomiao Huang3

  • 1Key Laboratory of Animal Molecular Nutrition Ministry of Education, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.

Nucleic acids research
|October 21, 2025
PubMed
概括
此摘要是机器生成的。

MouseOmics是一个新的数据库,集成了鼠标多omics数据,包括基因组,转录组和蛋白质组. 该资源通过提供全面的数据探索工具来支持医学和生命科学研究.

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Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
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相关实验视频

Last Updated: Jan 14, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
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Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
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Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells
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Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells

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科学领域:

  • 生命科学 生命科学
  • 基因组学就是基因组学.
  • 蛋白质组学是指蛋白质组学.
  • 代谢学 代谢学 代谢学

背景情况:

  • 小鼠是生命科学中至关重要的模型,特别是在发育生物学和多学科研究中.
  • 目前还没有针对鼠标多omics数据的全面,综合数据库.

研究的目的:

  • 建立MouseOmics,一个统一的数据库,集成各种鼠标多omics数据.
  • 为探索和分析鼠标多omics信息提供用户友好的工具.

主要方法:

  • 整合了来自21个基因组,584个转录体,285个蛋白质体,143个代谢体,296个金属体和5个Mus物种和52个杂交菌株的3个变异体的数据.
  • 开发了一个带有功能模块的网络界面,用于数据探索.
  • 嵌入式工具用于微卫星DNA识别 (MISAweb) 和途径/基因本体学丰富分析.

主要成果:

  • 成功建立了MouseOmics,一个全面的鼠标多omics数据库.
  • 实施了用户友好的勘探模块和专门的分析工具.
  • 启用了多omics数据的方便在线下载.

结论:

  • MouseOmics为医学和生命科学研究人员提供了不可或缺的资源.
  • 该数据库通过集成的多omics数据和工具,方便对小鼠生物学进行深入分析.
  • 定期更新将确保MouseOmics仍然是当前和有价值的资源.