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Updated: Jan 14, 2026

Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation
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酸激酶M2通过增强SNAP23介导的血小板外细胞和由此产生的NETosis促进静脉血栓形成

Manasa K Nayak1, Gagan D Flora1, Ivan Budnik1

  • 1Division of Hematology, Oncology, and Blood & Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA.

Blood advances
|October 21, 2025
PubMed
概括

在血小板中向酸盐激酶M2 (PKM2) 通过抑制中性粒细胞外细胞陷 (NET) 形成和血小板激活,减少深静脉血栓形成 (DVT). 这种代谢酶在DVT病理生物学中起着关键作用.

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