电针对高血压和认知障碍患者的微循环的影响:多中心随机对照试验的协议
Jian Wen1, XInlei Dong1, Xiaolin Chen1
1National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
JMIR research protocols
|October 21, 2025
概括
电可以通过调节微循环来改善高血压和认知障碍. 这项研究研究了它在患有这两种疾病的患者中的疗效,探索了潜在的机制.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 综合医学是一个整体的医学.
背景情况:
- 高血压是心血管疾病和轻度认知障碍 (MCI) 的关键危险因素.
- 微循环功能障碍与高血压和认知能力下降的并发症有关.
- 针作为高血压和MCI的治疗方法具有前景.
研究的目的:
- 评估电治疗高血压患者轻度认知障碍 (MCI) 的临床疗效.
- 通过调节微循环,研究电是否能改善高血压和认知功能.
主要方法:
- 一个多中心,单盲,随机对照试验,涉及252名患者.
- 三组:电针,假电针 (SEA) 和等候名单.
- 主要结果:认知功能的变化 (蒙特利尔认知评估);次要结果:血压,认知领域,血液动力学和微循环.
主要成果:
- 数据收集正在进行中,截至2025年1月1日,已有65名患者注册.
- 目前还没有进行数据分析.
- 预计2026年7月将获得完整的结果.
结论:
- 这项试验将比较电对SEA的疗效,以及对高血压与认知障碍等待名单的对照.
- 它旨在阐明电在这个患者群体中的微循环机制.
- 这些发现将支持对这些疾病的电治疗的进一步研究.
相关概念视频
02:07Blind Procedures
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...
01:11Blinding
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.