澳大利亚的侵入性肺炎球菌病:2013年和2014年
Kate Pennington1, Sanjay Jayasinghe2, Lizzie Gorrell3
1Enhanced IPD Surveillance Working Group, Australian Government Department of Health, Disability and Ageing, Canberra, Australian Capital Territory, Australia.
Communicable diseases intelligence (2018)
|October 21, 2025
概括
侵入性肺炎球菌病 (IPD) 的发病率在澳大利亚保持稳定,澳大利亚土著居民的发病率不成比例地高. 引入13肺炎球菌合疫苗 (13vPCV) 导致幼儿的IPD减少.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 侵入性肺炎球菌病 (IPD) 在全球范围内构成了重大公共卫生挑战.
- 肺炎球菌疫苗接种计划旨在减少IPD的负担.
- 监测数据对于监测疾病趋势和疫苗有效性至关重要.
研究的目的:
- 分析2013年至2014年期间澳大利亚IPD的流行病学.
- 评估13肺炎球菌合疫苗 (13vPCV) 对儿童IPD发病率的影响.
- 检查IPD血清型的趋势,特别是那些被23肺炎球菌多糖体疫苗 (23vPPV) 覆盖的成年人.
主要方法:
- 利用了2013年和2014年国家报告疾病监测系统 (NNDSS) 的数据.
- 计算了IPD的年龄标准化和非年龄标准化发病率.
- 分析了根据土著身份,年龄组和疫苗可预防的血清型的IPD病例率.
主要成果:
- 澳大利亚在2013年报告了1552例IPD病例,在2014年报告了1564例.
- 澳大利亚土著居民的IPD率是非土著澳大利亚人的6倍.
- 在13vPCV引入后,5岁以下儿童的IPD发病率在2013年从每10万人中从19.8下降到12.5,在2014年略有增加至14.1.
- 由23vPPV血清型引起的IPD的发病率在土著成年人 (50+) 和非土著成年人 (65+) 中下降.
- 2013年IPD的病例死亡率为8.6%,2014年为7.5%.
结论:
- 在2013-2014年期间,澳大利亚的IPD发病率保持相对稳定.
- 13vPCV疫苗在减少幼儿IPD方面表现出有效性.
- 印第安人和非印第安人之间存在IPD发病率的持续差异.
- 在老年人中23vPPV血清型的下降趋势需要持续监测.
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