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Updated: Jan 14, 2026

Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
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在确定酶抑制的IC50值时,对基质度的实际考虑

Stephen L Bearne1,2

  • 1Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.

Biochemistry and cell biology = Biochimie et biologie cellulaire
|October 21, 2025
PubMed
概括

确定最佳基质度可以增强酶抑制剂功效测试. 对于竞争性和线性混合型抑制剂,特定的基质水平最大限度地提高了抑制检测灵敏度.

关键词:
IC50 IC50 IC50 IC50 IC50 IC50 IC50 IC50 IC50 IC50 IC50 IC50 IC50酶抑制抑制酶的抑制.酶动力学 酶动力学最初的速度差异不同.最佳的基质度是最佳的基质度.

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