肠道神经系统 肠道神经系统
David R Linden1, Keith A Sharkey2
1Enteric Neuroscience Program, Mayo Clinic, Rochester, MN 55905, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
Current biology : CB
|October 21, 2025
概括
肠道神经系统 (ENS) 位于肠道,是一个复杂的网络,神经元数量与脊髓一样多. 这种"第二大脑"可以独立于中央神经系统运作.
科学领域:
- 神经科学是一个神经科学.
- 胃肠病学 胃肠病学
背景情况:
- 肠道神经系统 (ENS) 是自主神经系统的一个独立部分,位于胃肠道 (GI) 管壁内.
- 它包含大量的神经元,相当于脊髓.
- 脑内神经系统的一个关键特征是它的自主性,它独立于中枢神经系统 (CNS) 运作.
研究的目的:
- 突出ENS独特的结构和功能特性.
- 强调ENS独立运作的能力.
- 为了强调ENS在神经系统的更广泛背景中的重要性.
主要方法:
- 审查关于ENS的现有文献.
- 在ENS和脊髓中对神经元数量的比较分析.
- 对ENS自主性的功能评估.
主要成果:
- 肠神经系统包含一个神经元群体,相当于脊髓.
- 在没有中枢神经系统输入的情况下,ENS表现出显著的功能能力.
- 肠道神经系统在胃肠道功能中起着至关重要的作用.
结论:
- 肠道神经系统是一个高度复杂和集成的神经网络在肠道.
- 它的独立功能能力使其成为肠道健康的关键组成部分.
- 对ENS进行进一步的研究有可能有助于理解和治疗胃肠道疾病.
相关概念视频
Enteric Nervous System: Regulation of GI Motor Activity
1.7K
The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
1.7K
Nerve Supply of the GI Tract
3.3K
The neuronal supply to the gastrointestinal (GI) tract is essential for regulating various functions, including digestion, absorption, and movement of food. This intricate network of nerves is known as the enteric nervous system (ENS), often referred to as the "second brain" of the body.
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of...
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of...
3.3K
Physiology of Enteric Nervous System and Gut Health
858
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
858
Neural Regulation
43.1K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.1K
Functional Divisions of the Nervous System
8.0K
The nervous system, responsible for sensing, integrating, and responding to various stimuli, is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The PNS has two functional divisions: the sensory or afferent division and the motor or efferent division.
The sensory division transmits information from sensory receptors in the body to the CNS. It provides the CNS with knowledge about somatic senses (such as tactile, thermal, pain, and proprioceptive sensations)...
The sensory division transmits information from sensory receptors in the body to the CNS. It provides the CNS with knowledge about somatic senses (such as tactile, thermal, pain, and proprioceptive sensations)...
8.0K
Autonomic Nervous System: Overview
7.3K
The human nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and spinal cord, while the PNS contains nerve cells, clusters of nerve cells, and the sensory receptors that are outside the CNS. The PNS has two types of nerve cells: sensory (afferent) and motor (efferent). Sensory cells send signals to the CNS from receptors, and motor cells carry signals from the CNS to organs, muscles, and...
7.3K


