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Updated: Jan 6, 2026

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
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肠道细菌通过减少性OsrABC途径代谢天然和合成类固醇激素

Christian Jacoby1, Kaylie Scorza1, Lia Ecker1

  • 1Duchossois Family Institute, University of Chicago, Chicago, IL 60637, USA; Department of Microbiology, University of Chicago, Chicago, IL 60637, USA.

Cell host & microbe
|October 21, 2025
PubMed
概括

肠道细菌Clostridium steroidoreducens通过OsrABC通路使类固醇激素失活. 这种微生物作用可以降低抗炎药物的有效性,如普雷尼索隆.

关键词:
克罗恩氏病 克罗恩氏病是什么?铁-S 类风味酶.药物的生物可用性.葡萄糖皮质醇的新陈代谢我们的肠道微生物组.微生物组与药物相互作用普雷迪尼索隆 (prednisolone) 是一种药物.类固醇激素类激素类固醇激素的产生

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