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在酒精性肝损伤中,BRD2通过NF-κB通路促进炎症和脂质积累

Juanjuan Li1, Haidi Li2, Miao Cheng2

  • 1School of Mental Health and Psychological Sciences, Laboratory of Molecular Neuropsychiatry, Anhui Medical University, Hefei 230032, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmaceutical Sciences, Anhui Medical University, Hefei 230032, China; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, Hefei, China.

Biochemical pharmacology
|October 21, 2025
PubMed
概括

含甲基蛋白2 (BRD2) 在酒精性肝病 (ALI) 中驱动炎症和肝损伤. 在巨细胞中减少BRD2可缓解肝损伤和脂质积累,这表明BRD2是治疗点.

关键词:
酒精性肝损伤导致的肝损伤这就是BRD2的原因.炎症 炎症是一种炎症.脂质代谢 脂质的代谢巨细胞是一个巨细胞.通过NF-κB路径.

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