环CHD6编码的216aa蛋白的相分离促进了结直肠癌的转移

Xuan Lai1, Manke Zhang2, Yinjun He3

  • 1Department of Pathology and International Institutes of Medicine, The Fourth Affiliated Hospital (Yiwu), Zhejiang University School of Medicine, Hangzhou, China; Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Hangzhou, China.

概括

一种新发现的蛋白质,circCHD6-216aa,通过形成核凝结物驱动结直肠癌转移. 它通过积极的反循环和通过通过核相互作用促进CD44转录来增强癌症的进展.

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