由于尿液的高放射性而导致的双边低积累膀人工物18F-FDG PET/CT
Yasutaka Ichikawa1, Yoya Tomita2, Kengo Hashizume2
1Department of Radiology, Mie University Hospital, Tsu, Mie, Japan yasutaka@med.mie-u.ac.jp.
Journal of nuclear medicine technology
|October 21, 2025
概括
在18F-FDG PET/CT扫描中,使用非TOF OSEM重建的双边低积累膀人工物发生在35%的病例中. 飞行时间 (TOF) 和贝叶斯惩罚概率 (BPL) 方法显著减少了这些工件.
科学领域:
- 核医学是一种核医学.
- 放射性药理学 是一种放射性药理学.
- 医疗成像医学成像
背景情况:
- 在18F-FDG PET/CT扫描中,双边低积累的膀人工物具有临床意义,但不太了解.
- 在例行检查中,导致这些文物出现的因素需要全面研究.
研究的目的:
- 在临床18F-FDG PET/CT扫描中确定双边低积累膀器件的患病率.
- 为了确定与这些文物发生相关的因素.
主要方法:
- 112名接受18F-FDG PET/CT.的患者的回顾性评估.
- 使用4种方法进行PET图像重建:OSEM (有/没有TOF) 和BPL (有/没有TOF),对于非TOF的OSEM,有分散校正 (SC) 变化.
- 幻影实验用于评估放射性和形状对文物发生的影响.
主要成果:
- 与非TOF OSEM (34.8%) (P < 0.001) 相比,TOF OSEM (6.3%),非TOF BPL (2.7%) 和TOF BPL (0%) 的文物发生率明显较低.
- 在没有SC的图像上也存在文物.
- 在有人工物患者中,膀中位数SUVmax较高 (59.8对28.5;P<0.001);幻影研究显示,矩形模型中人工物强度增加,放射性更高.
结论:
- 在非TOF OSEM重建的18F-FDG PET/CT扫描中,双边低积累膀工件发生在35%左右.
- 人工物发生与尿膀放射性相关,并受到身体形状的影响,独立于SC.
- TOF和BPL重建方法有效地减少了文物流行.
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