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Updated: Jun 17, 2026

Probe-based Real-time PCR Approaches for Quantitative Measurement of microRNAs
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在细胞中高度敏感和定量检测microRNA-21,使用双脚DNA步行者基的放射测量光传感器

Wenting Wei1, Han Lin2, Kuniharu Ijiro2

  • 1Graduate School of Life Science, Hokkaido UniversityKita 10, Nishi 8, Kita-Ku, Sapporo 060-0810, Japan.

Analytical chemistry
|October 21, 2025
PubMed
概括

这项研究引入了一种用于精确检测微RNA (miRNA) 的新型DNA步行者系统. 创新的设计对环境变化进行了校正,提高了用于癌症生物标志物研究的复杂生物样本的准确性.

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相关概念视频

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...