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Updated: Jan 14, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

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过度表达P-选择素会通过炎症受体介导的增殖和分化损害造血干细胞恒常性

Wei He1, Huandi Qiu2, Yunyu Feng1

  • 1State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.

Cell death & disease
|October 21, 2025
PubMed
概括

皮选择素 (SELP) 通过促进炎症和基因组不稳定性,驱动血造干细胞 (HSC) 的衰老和衰竭. 向P-选择素可能会恢复HSC功能,并对抗白血病干细胞.

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