链接色彩成像改善了在多中心随机背靠背试验的全结肠镜检查中多错误率
Ryo Shimoda1, Daisuke Yamaguchi2,3, Kazutoshi Hashiguchi4
1Department of Endoscopic Diagnostics and Therapeutics, Saga University Hospital, 5-1-1 Nabeshima, Saga, 849-8501, Japan. shimodar@cc.saga-u.ac.jp.
Scientific reports
|October 21, 2025
概括
与白光成像 (WLI) 相比,链接色彩成像 (LCI) 显著降低了结直肠聚错误率. 此外,LCI还可以提高腺瘤检测率,特别是在小腺瘤中.
科学领域:
- 胃肠病学 胃肠病学
- 内镜成像技术的成像
- 结肠直肠癌查 结肠直肠癌查
背景情况:
- 胃肠道瘤需要早期检测才能得到有效的治疗.
- 白光成像 (WLI) 是结肠镜的标准,但在检测微妙的病变方面存在局限性.
- 链接色彩成像 (LCI) 是为了增强胃肠道异常的可视化而开发的.
研究的目的:
- 用链接色彩成像 (LCI) 与白光成像 (WLI) 来比较结直肠多的错误率.
- 评估LCI对腺瘤检测率 (ADR) 的影响.
主要方法:
- 一个多中心的,随机的,背靠背的双重结肠镜研究.
- 患者被分配到WLI跟随LCI (WLI-LCI组) 或LCI跟随WLI (LCI-WLI组).
- 主要结局:每名患者的聚合体错误率 (PMR-PP);二次结局:腺瘤检测率 (ADR).
主要成果:
- 在LCI-WLI组 (9.3%) 与WLI-LCI组 (20.6%) 相比,每位患者的多错误率 (PMR-PP) 显着较低.
- 在横向和下行结肠和直肠中,LCI显示的PMR-PP比WLI低.
- 小型腺瘤 (<5毫米) 的腺瘤检测率 (ADR) 与LCI (38.2%) 比WLI (29.1%) 高.
结论:
- 结合色彩成像 (LCI) 在减少结肠直肠多错误率方面优于白光成像 (WLI).
- LCI增强了腺瘤的检测能力,特别是小腺瘤和特定的结肠细分.
- 在改善结直肠癌查和诊断的有效性方面,LCI显示出前景.
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