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Updated: Jan 14, 2026

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
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Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid

Published on: September 20, 2017

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通过使用计算和实验方法,通过冷解固体分散增强赛莱可西布的可溶性

Fatima Rasool1, Ayesha Naseem2, Huma Javaid2,3

  • 1Punjab University College of Pharmacy, Faculty of Pharmacy, University of the Punjab, Lahore, 54590, Pakistan. fatima.pharmacy@pu.edu.pk.

Scientific reports
|October 21, 2025
PubMed
概括

这项研究提高了使用基烯基β-环氧化 (HP-βCD) 固体分散的赛莱科西布 (CLX) 溶解性和溶解性. 优化的HP-βCD系统显著改善了CLX口服生物可用性.

关键词:
切莱科克西布 (Celecoxib) 是一种药物.药物聚合物兼容性 药物聚合物兼容性惠普-β-循环德克斯特林 (HP-βCD) 是一种HP-β-循环德克斯特林.软化液体固体分散液.分子模拟分子模拟固体分散的分散方式可溶性增强 提高可溶性

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