coPERCIST:人工智能辅助的PET-CT反应评估
Elin Trägårdh1,2, Måns Larsson3, Olof Enqvist3,4
1Department of Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Inga Marie Nilssons G 49, 205 02, Malmö, Sweden. Elin.tragardh@med.lu.se.
European journal of nuclear medicine and molecular imaging
|October 21, 2025
概括
本研究介绍了coPERCIST,这是一种人工智能工具,可以使用PERCIST标准半自动化[18F]FDG PET-CT分析癌症治疗反应. 人工智能系统简化了评估,提供准确和可重复的结果,减少了审查时间.
科学领域:
- 在瘤学瘤学.
- 医疗成像医学成像
- 人工智能的人工智能
背景情况:
- 固体瘤中的PET反应标准 (PERCIST) 1.0标准化了PET-CT对[18F]氧糖 ([18F]FDG) 的反应评估.
- 手动 PERCIST 分析是复杂且耗时的,这限制了其临床应用.
研究的目的:
- 介绍coPERCIST,一个用于RECOMIA平台的AI辅助模块.
- 为 [18F]FDG PET-CT.半自动化和简化PERCIST分析.
主要方法:
- coPERCIST自动化了器官细分,背景量化,病变检测,SULpeak计算和纵向比较.
- 一种具有不确定性估计的新型图像对齐方法可以确保精确的损伤跟踪.
- 该系统在58名癌症患者身上进行了评估,每个患者进行了两次PET-CT扫描.
主要成果:
- 在所有情况下,AI建议的门计算的利息量都是准确的.
- 在所有130个评估的病变中都实现了精确的解剖学对齐.
- 双向SULpeak量化准确率为95%,大多数情况下在不到一分钟的时间内进行了审查.
结论:
- 使用coPERCIST进行人工智能辅助的PERCIST评估是可行的,并且显示出有希望的准确性.
- coPERCIST促进可再生癌症治疗反应评估.
- 该工具在RECOMIA平台上免费提供给研究人员.
![PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F67717.jpg&w=3840&q=50)
相关概念视频
01:29Positron Emission Tomography
6.9K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.9K
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
493
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
493
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
402
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
402
01:28Imaging Studies for Cardiovascular System V: CT
279
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
279
01:10Computed Tomography
8.0K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
8.0K