个人水平环境温度对高血压患者的门诊血压的短期影响:多人面板研究
Hanrui Liu1,2, Zhennan Lin3,4, Xueli Yang5
1Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Journal of the American Heart Association
|October 22, 2025
概括
较低的个人环境温度 (PET) 会增加高血压患者的血压 (BP),特别是女性和血压不受控制的患者. 保持血压控制对于管理温度相关的血压变化至关重要.
科学领域:
- 环境健康 环境健康
- 心血管医学 心血管医学
- 流行病学 流行病学
背景情况:
- 对于高血压患者的个人环境温度 (PET) 和门诊血压 (BP) 的证据有限.
- 环境温度和BP之间的反向关系是已知的,但个人层面的数据很少.
研究的目的:
- 研究高血压患者的个人环境温度 (PET) 和门诊血压 (BP) 之间的关联.
- 探索PET对血压变化和生理节律在这个人群中的影响.
主要方法:
- 一项三阶段小组研究,涉及277名高血压患者,心血管风险中等至高.
- 使用个人便携式设备持续监测PET和门诊血压.
- 一般化的线性和添加混合效应模型用于分析关联和暴露-反应曲线,并进行子组分析.
主要成果:
- 减少PET与增加的门诊血压密切相关,特别是白天的缩血压.
- 血压变化和昼夜血压指标 (早晨血压升,夜间血压下降) 与PET有显著联系.
- 在女性和患有无控制血压的个体中,相关性更强,突出显示了显著的相互作用效应.
结论:
- 短期暴露于较低的PET对高血压患者的门诊血压指标产生不利影响.
- 有效的血压控制在减轻温度下降对高血压管理的负面影响方面起到有益的作用.
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