相关实验视频

Updated: Jan 14, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex

Published on: July 4, 2018

在机器人辅助腹腔镜前列腺切除术期间的痛感水平 (NOL^®) 测量的变化 - 一个单心的回顾性分析

Julia Heiden¹, Jonas Hoefermann¹, Katharina Hoeter¹

¹Department of Anaesthesiology, University Medical Center Mainz, Mainz, Germany.

BMC anesthesiology

|October 22, 2025

概括

诺尔指数显示机器人辅助前列腺切除术期间的变化,随着止痛减小,随着手术刺激增加. 这种感知监测可能有助于优化麻醉期间的疼痛管理.

科学领域:

麻醉学麻醉学
手术监测手术监测
疼痛管理疼痛管理

背景情况:

在麻醉期间不充分的止痛可以导致并发症.
在常规的临床实践中,缺乏对抗nociception的客观评估.
了解术后事件对监测的影响至关重要.

研究的目的:

为了评估NOL-Index在机器人辅助腹腔镜前列腺切除术期间对特定刺激的反应.
评估在麻醉中感觉监测的临床效用.

主要方法:

对33名接受机器人辅助腹腔镜前列腺切除术的患者的回顾性分析.
在五种刺激中测量了NOL-Index,BIS,心率和MAP.
刺激包括胃管放置,导管,皮管,的Trendelenburg和sufentanil的管理.

主要成果:

随着capnoperitoneum的使用,NOL指数显著增加 (p < 0.001).
随着Trendelenburg (p = 0.002) 和sufentanil (p < 0.001) 的急剧出现,NOL指数显著下降.
在胃管或尿导管放置期间没有观察到显著的NOL-Index变化. 国际清算银行没有显示任何相关偏差.

结论:

在机器人辅助腹腔镜前列腺切除术期间,NOL-Index显示了特征性变化.
结果为前性研究提供了基础,研究可感知监测的临床相关性.
无感觉监测可能有助于优化止痛疗法和患者的结果.

关键词:

麻醉麻醉是一种麻醉.没有感知水平指数指数.没有感觉监测监测器.非侵袭性监测是一种非侵袭性监测.机器人辅助手术是一种机器人辅助的手术.

更多相关视频

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

Published on: January 25, 2022

相关概念视频

Nociception

Nociception

Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...