更高的预后营养指数与老年严重病的外科手术患者需要置换治疗的需求相反相关
Qi Liu1, Simin Li1, Hailin He1
1Department of Cardiac Surgical Intensive Care Unit, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, No. 106, Zhongshan 2Nd Road, Guangzhou City, Guangdong Province, 510080, People's Republic of China.
BMC surgery
|October 22, 2025
概括
在需要重症监护的老年手术患者中,预后营养指数 (PNI) 水平较高,与较低的替代疗法 (RRT) 需求有关. 这一发现凸显了PNI作为重症患者RRT的潜在指标.
科学领域:
- 关键护理医学 关键护理医学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 外科手术的结果
背景情况:
- 急性损伤 (AKI) 需要置换疗法 (RRT) 是老年手术患者的严重并发症,导致高死亡率和医疗费用.
- 预后营养指数 (PNI) 是衡量营养和免疫状况的指标,其与该人群中RRT需求的关联尚未得到充分探索.
研究的目的:
- 调查预后营养指数 (PNI) 与 65 岁及以上严重病情的手术患者替代疗法 (RRT) 的需求之间的关系.
主要方法:
- 在ICU中对3,406名老年手术患者进行了二次分析.
- 预后营养指数 (PNI) 被计算在ICU入院时. 患者被分为PNI第三类.
- 使用多变量逻辑回归,子组分析和受限立方线来评估PNI和RRT需求之间的关联.
主要成果:
- 在对共变量进行调整后 (OR=0.95每增加10个单位) 发现PNI与RRT需求之间存在显著的反向关联.
- 与低端患者相比,中等和高端PNI患者的RRT风险逐渐降低 (趋势P<0.0001).
- 限制立方线分析表明了线性关系,而2.59的E值表明了对未测量的混的稳定性.
结论:
- 预后营养指数 (PNI) 水平的升高与严重病重的老年外科手术患者的置换疗法 (RRT) 需要相反相关.
- 在这种患者群体中,PNI可以作为预测RRT需求的有价值指标.
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