一种罕见的外周骨髓质纤维瘤病例,表现为大牙质量
Yu Du1,2, Ping Yang3,4, Nan Xie1,2
1Hospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
BMC oral health
|October 22, 2025
概括
周围骨髓质纤维瘤 (AF) 是一种罕见的牙瘤. 这一案例突出了其诊断和成功的保守性外科切除,强调了用于准确识别的组织病理学.
科学领域:
- 口腔和面病理学 口腔和面病理学
- 牙发生性瘤 牙发生性瘤
- 牙上的病变 牙上的病变
背景情况:
- 骨髓质纤维瘤 (AF) 是一种罕见的良性牙瘤,具有表皮和介质细胞组成部分,通常在下.
- 发生在牙软组织中的外周AF非常罕见,并且经常被误诊为反应性病变.
- 准确的诊断依赖于组织病理学确认,因为其与其他牙质量具有临床相似性.
研究的目的:
- 报告一个罕见的外周骨髓质纤维瘤 (AF) 病例在 palatal gingiva.
- 为了说明外围AF的诊断挑战和管理.
- 强调组织病理学和免疫组织化学在诊断和管理这种罕见疾病中的作用.
主要方法:
- 分析了一个34岁的女性患有外周AF的病例,该病例呈现了 palatal gingival 质量.
- 临床和放射评估 (全景成像,CBCT) 排除了骨参与.
- 进行了手术切除,根平和软组织重建,随后进行了组织病理学和免疫组织化学分析 (Ki-67,BRAF).
主要成果:
- 组织病理学证实了带有特征性上皮和介质细胞组件的外周AF.
- 免疫组织化学显示基-67扩散指数低,BRAF为负,支持良性性质.
- 20个月的随访显示没有复发,牙有很好的愈合和保存的结构.
结论:
- 在不同寻常的牙质群体的差异诊断中应考虑外围AF.
- 组织病理学和免疫组织化学分析对于准确的诊断和治疗计划至关重要.
- 保守的手术切除与细致的设计产生了有利的功能和美学结果的外围AF.
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