米达佐拉姆在门诊儿科牙科的有效性:系统性审查
Judit Rabassa-Blanco1,2,3, Pau Cahuana-Bartra1,2,3, Yndira González-Chópite1,3
1Department of Dentistry, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain.
概括
米达佐拉姆是一种有效和安全的口服镇静剂,用于接受牙科手术的儿童,显著减少焦虑和改善合作. 推剂量为0.3-0.5毫克/公斤,建议在与其他药物一起使用时进行监督.
科学领域:
- 儿科牙科 儿科牙科
- 药理学 药理学是指药理学的学科.
- 镇静技术 镇静技术
背景情况:
- 管理儿童牙科患者的焦虑和行为对于成功治疗至关重要.
- 米达佐拉姆是一种常用于各种医疗领域的镇静剂.
研究的目的:
- 系统地审查米达佐拉姆在门诊儿科牙科中适度镇静的疗效,优势和不良影响.
- 分析其在常规牙科手术中遇到行为或合作挑战的儿童中的使用情况.
主要方法:
- 在MEDLINE/PubMed,Scopus和Cochrane图书馆进行系统的文献搜索,直到2024年9月,遵守PRISMA标准.
- 包括涉及0-16岁的行为障碍儿童接受局部麻醉下简单的恢复性牙科手术的研究.
- 排除对全身麻醉前期治疗,特殊需要患者或没有生命体征监测的患者的研究.
主要成果:
- 分析了28项涉及4374名儿童 (2-14岁) 的研究,其中大多数显示偏差风险较低.
- 米达佐拉姆,口服,鼻内或口腔,有效地减少了焦虑和改善了合作,对未来的访问有好处.
- 副作用是罕见和轻微的,包括恶心,吐和矛盾反应.
结论:
- 口服米达佐 (0.3-0.5 mg/kg) 是有效和安全的适度镇静在儿科牙科手术,可靠地减少焦虑和加强合作.
- 建议在将米达佐拉姆与其他镇静剂结合使用时由麻醉师进行监督,以确保患者的安全.
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