亚急性疼痛,慢性疼痛和睡眠障碍之间的关系:基于NHANES (2009-2010) 的跨部分研究
Yanlin Yang1, Gaohui Wu2, Minxian Wang3
1Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Brain and behavior
|October 22, 2025
概括
与亚急性疼痛相比,慢性疼痛显著增加了睡眠障碍的可能性. 建议对亚急性疼痛进行早期干预,因为它与睡眠障碍有关.
科学领域:
- 疼痛医学 医学 疼痛医学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 慢性疼痛 (CP) 和亚急性疼痛 (SAP) 是普遍存在的疾病.
- 睡眠障碍 (SD) 经常与疼痛并存,但疼痛持续时间对SD的影响尚不清楚.
研究的目的:
- 研究疼痛持续时间 (CP与SAP) 与睡眠障碍 (SD) 之间的关联.
- 通过止痛药的使用和疼痛强度来探索潜在的效果修改.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2009-2010年) 的横截面分析.
- 使用计算机辅助个人采访 (CAPI) 进行疼痛和睡眠障碍评估的结构化采访.
- 多变量逻辑回归模型用于确定疼痛持续时间和SD之间的关系.
主要成果:
- 与SAP (OR = 1.85) 相比,患有CP的人患SD的可能性高出85%.
- 特定的疼痛特征,如休息时恶化或从睡眠中醒来,与SD有很强的关联.
- 对于止痛药的使用或疼痛强度,没有发现显著的相互作用效应.
结论:
- 亚急性和慢性疼痛似乎都是睡眠障碍的独立风险因素.
- 这些发现支持了对亚急性疼痛的早期干预的必要性,以减轻睡眠障碍.
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