系统性自身免疫性风湿性疾病中的性功能障碍:患病率,影响和管理策略
Monisha In1, Nilanjana Dutta2, Harshwardhan Patil1
1Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, India.
Mediterranean journal of rheumatology
|October 22, 2025
概括
性功能障碍 (SD) 在全身性自身免疫性类风湿性疾病 (SARD) 中很常见,影响高达90%的患者. 解决SD需要一个多学科的方法,包括疼痛管理和心理支持.
科学领域:
- 类风湿病学 类风湿病学
- 性医学性医学性医学性医学
- 生活质量研究 研究 生命质量研究
背景情况:
- 系统性自身免疫性类风湿性疾病 (SARDs) 显著损害患者的生活质量,特别是性健康.
- 性功能障碍 (SD) 在临床环境中经常被忽视,尽管它具有深远的影响.
- 在SARD中导致SD的因素包括疼痛,疲劳,关节硬,荷尔蒙变化和心理困扰.
研究的目的:
- 审查诊断为SARDs的患者中SD的流行率,影响和管理策略.
- 在特定疾病中检查SD:全身性红斑狼 (SLE),类风湿性关节炎 (RA),缩性脊柱炎 (AS),Sjögren病 (SjD),全身性硬化症 (SSc) 和纤维肌痛综合征 (FMS).
主要方法:
- 使用主要科学数据库 (PubMed,科学网,Scopus) 进行了系统的文献审查.
- 在SARD中报告SD的相关研究被使用特定的MeSH术语识别出来.
- 性功能通常使用经过验证的仪器进行评估,例如女性性功能指数 (FSFI) 和国际勃起功能指数 (IIEF).
主要成果:
- 在SARD中,SD的患病率因疾病类型和性别而有很大差异 (30%-90%).
- 在SLE (高达90%的女性),RA (30%-70%),AS (41%-58%的男性勃起功能障碍),SjD (超过56%的女性),SSc (80%的男性勃起功能障碍) 和FMS (63%) 中报告了SD的高率.
- SD的主要驱动因素包括慢性疼痛,抑郁症,阴道干燥,纤维化和心理负担.
结论:
- SD是SARD患者中非常普遍且未得到充分解决的问题.
- 有效的管理需要一个多学科的战略.
- 治疗应整合疼痛控制,心理支持,激素干预和患者教育.
相关概念视频
01:29Autoimmune Disorders
1.5K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
1.5K
01:20Disorders of the Male Reproductive System
4.0K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
4.0K
01:21Rheumatic Heart Disease III: Medical Management
282
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
282
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
476
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
476
01:26Nephrotic Syndrome II : Assessment and Medical Management
197
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
197
01:20Rheumatic Heart Disease IV: Nursing Management
264
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
264