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与运动神经传导研究相关的下肢感觉神经动作潜力 (SNAP) 幅度侧对侧差异的评估

Handan Uzunçakmak-Uyanık^1,2, Merve Melodi Çakar³, Refah Sayın¹

¹Neurology, Ufuk University, Ankara, TUR.

|October 22, 2025

概括

如果考虑到部运动神经的差异,部和表面部神经传导研究中的侧对侧差异可能是正常的. 这有助于减少神经传导研究中的假阳性诊断.

科学领域:

神经生理学神经生理学
临床肌电图学临床肌电图学
生物医学工程生物医学工程

背景情况:

神经传导研究 (NCS) 对于诊断外围神经障碍至关重要.
解剖学变化和技术因素可能会导致NCS的显著侧对侧振幅差异.
这些差异可能导致误解和错误的阳性诊断.

研究的目的:

为了确定侧向侧幅度差异的正常参考极限,在上部和表面部感觉神经动作潜力 (SNAP) 中.
为了研究下肢运动神经 (复合肌肉动作潜力-CMAP) 和SNAP振幅之间的关联.
减少NCS中错误阳性诊断的发生率.

主要方法:

50名健康成年人接受了NCS测量下肢CMAP和SNAP幅度.
分析了两侧差异,上限定义为平均值+2个标准偏差.
用皮尔森相关性和线性回归来评估CMAP和SNAP幅度之间的关系.

主要成果:

在内CMAP和内SNAP (r=0.451) 之间以及内CMAP和表面内SNAP (r=0.304) 之间观察到显著的正相关性.
内CMAP振幅是外表和表面内SNAP振幅的显著预测指标.
正常的表面和表面腹SNAP差异被定义为分别高达7.76μV和6.7μV,当腹CMAP侧对侧差异为≤4.04mV时.

结论:

将体CMAP振幅不对称性纳入下肢SNAP差异的解释可以提高诊断准确性.
这种方法可能会显著降低NCS中错误阳性发现的比率.
为了可靠的电诊断测试,考虑运动神经的影响,建立对侧对侧SNAP差异的规范性数据至关重要.

关键词:

解剖学变化的变化.不对称的不对称性侧对侧的幅度差异差异.表面腹部感觉神经的感觉神经.在外表神经上,外表神经

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