与水相关的眼病:在资源有限的环境中,免疫能力强的患者患有形角膜炎和复发性角膜炎
Christian García-Mera1, Daniela Yosa2
1Emergency Department, Instituto del Cáncer SOLCA Cuenca, Cuenca, ECU.
Cureus
|October 22, 2025
概括
与水相关的眼病 (MPXROD) 可以导致复发的视力丧失. 这一案例表明,用抗病毒药物,类固醇和局部胰岛素进行个性化治疗可以控制严重的MPXROD爆发.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 与水相关的眼病 (MPXROD) 是一种罕见但严重的水病毒 (MPXV) 感染的并发症.
- 眼睛的干扰可以从轻微的结膜炎到严重的角膜炎和脑膜炎,可能导致视力受损.
研究的目的:
- 在一个免疫能力强的个体中描述MPXV感染后出现的复发性角膜炎的病例.
- 为了突出管理MPXROD的挑战,当第一线抗病毒疗法无法使用时.
- 强调个性化治疗策略的作用,包括辅助疗法,在维护视力.
主要方法:
- 一个28岁的免疫能力强的男性患有MPXROD的案例报告.
- 诊断证实通过前腔体检查识别MPXV.
- 治疗包括口服瓦拉西克洛维尔,逐渐减少的皮质类固醇,眼部滑剂和复合局部胰岛素,用于复发的角膜炎爆发.
主要成果:
- 患者在急性MPXV感染期间出现视力下降和角膜.
- 对于疑似疹性角膜炎的初始治疗解决了,但留下了一个 stromal 白血瘤.
- 复发性角膜炎通过抗病毒药物,皮质类固醇,支持性护理和局部胰岛素的组合有效管理.
结论:
- MPXROD可以引起复发性角膜炎,即使在免疫能力强的患者中也是如此.
- 当标准抗病毒选择有限时,个性化治疗至关重要.
- 在严重的MPXROD病例中,诸如局部胰岛素之类的辅助疗法可能对视力保护和角膜愈合至关重要.
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