在患有 kongenital cytomegalovirus 感染的无症状儿童中评价嗅觉功能
Chrysanthi-Eleni Loizou1, Sofia Karagiannidou1, Garyfallia Syridou1
1Third Department of Paediatrics, University General Hospital "Attikon", National and Kapodistrian University of Athens, Athens, GRC.
Cureus
|October 22, 2025
概括
在出生时无症状的儿童中,先天性细胞巨乳病毒 (cCMV) 感染不会影响他们的嗅觉. 这项研究发现,cCMV感染儿童和健康对照人群之间嗅觉功能没有差异.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 在全球范围内,先天性细胞巨乳病毒 (cCMV) 是最常见的先天性感染.
- cCMV可以导致长期的健康问题,即使在婴儿出生时没有症状.
- 关于cCMV对出生时无症状儿童的长期影响的数据有限,特别是在嗅觉功能方面.
研究的目的:
- 评估出生时无症状的cCMV感染儿童的嗅觉功能.
- 为了比较这些孩子的嗅觉功能与年龄和性别相匹配的健康对照.
主要方法:
- 一项涉及63名儿童 (5岁及以上) 的病例控制研究,分为cCMV感染 (病例) 和健康 (对照) 组.
- 病例和对照人群在年龄和性别方面以1:2的比例匹配.
- 用经过验证的U-Sniff气味识别测试 (儿童身份测试) 来评估嗅觉功能.
主要成果:
- 在cCMV感染儿童和健康对照人群之间,嗅觉功能或百分点得分没有发现统计学上显著的差异.
- 根据年龄组 (5-8岁和9-11岁) 和COVID-19感染史分层的子分析也显示,嗅觉功能没有显著差异.
- 这些发现在不同年龄层和COVID-19暴露状态中保持一致.
结论:
- 在出生时无症状的儿童中,先天性细胞巨乳病毒感染似乎不会损害嗅觉功能.
- 这些孩子的嗅觉系统的功能与他们的健康同龄人相比较.
- 进一步的研究可能会在这个人群中探索其他感官或认知功能.
更多相关视频
09:03Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
5.5K
05:53Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
15.5K
相关概念视频
Olfactory Receptors: Location and Structure
11.2K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
11.2K
Olfaction
48.1K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
The olfactory receptors are embedded in the cilia of the...
48.1K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
3.1K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
3.1K
