在皮肤植物病中出现的抗真菌抵抗:来自北印度的临床菌学研究
Anushka Lohariwala1, Sanjeev Gupta1, Narinder Kaur2
1Dermatology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar (Deemed to be University), Ambala, IND.
Cureus
|October 22, 2025
概括
皮肤植物病是一个日益严重的公共卫生问题,通常是慢性和复发性的,特别是在农村人口中. 新兴的抗真菌耐药性对常见的治疗方法,如可纳和terbinafine需要更好的遵守和监测.
科学领域:
- 皮肤病学 皮肤病学
- 菌类学 菌类学是指菌类学.
- 公共卫生 公共卫生
背景情况:
- 皮肤植物病是一种表面的真菌感染,越来越多地被认为是公共卫生挑战.
- 慢性和复发病例正在增加,可能是由于抗真菌耐药性和药物滥用.
研究的目的:
- 评估皮肤植物病患者的人口统计和临床特征.
- 评估治疗史,复发率和抗真菌耐药性模式.
主要方法:
- 一项对130名临床诊断为皮肤植物病的患者的观察性研究.
- 数据收集包括人口统计数据,临床表现 (皮肤细胞瘤严重性得分),治疗史和复发情况.
- 进行了真菌培养和抗真菌敏感性测试.
主要成果:
- 受影响最严重的群体是31-45岁 (42.2%),男性占主导地位 (57.8%). 农村,不受过教育的个人和家庭主妇/学生是最常见的.
- 复发率很高 (92.2%),即使是轻微的严重程度. 肉是最常见的类型 (87.8%).
- 特里科菲顿 (Trichophyton mentagrophytes) 是主要的物种 (75.7%). 观察到对可纳 (85.6%) 和特比纳 (60%) 的耐药性,但对伊特拉可纳,可纳和格里索富尔文的敏感性.
结论:
- 皮肤植物病仍然是一个重要的公共卫生问题,因为慢性和复发.
- 不合理的药物使用和新兴的抗真菌耐药性是关键问题.
- 改善治疗遵守性和定期监测耐药性模式至关重要.
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