中国和G20的肝癌负担趋势:使用GBD 2021年的比较分析
Xiaodi Ma1, Lining Jiang2, Bing Han3
1Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China.
Frontiers in oncology
|October 22, 2025
概括
在中国和G20国家,肝癌率下降,但绝对负担增加. 肥胖,吸毒和高禁食血葡萄糖的风险不断增加,需要加强预防策略.
科学领域:
- 全球健康 全球健康
- 癌症流行病学 癌症流行病学
- 公共卫生政策 公共卫生政策
背景情况:
- 肝癌是一个重大的全球健康挑战.
- 了解区域趋势和风险因素对于有效的公共卫生干预至关重要.
研究的目的:
- 比较中国与G20国家 (1990-2021) 的肝癌趋势和危险因素.
- 告知有针对性的预防策略和对肝癌控制的资源配置.
主要方法:
- 利用2021年全球疾病负担 (GBD) 数据进行肝癌分析.
- 员工加入点回归来评估趋势 (APC,AAPC) 和因子归因的分解分析.
- 计算的年龄标准化发病率 (ASIR),死亡率 (ASMR) 和根据残疾调整的寿命年数 (ASDR) 率.
主要成果:
- 从1990年到2021年,中国和G20国家的肝癌率下降,中国的下降幅度更大 (2000年至2005年).
- 人口老龄化是增加率的主要驱动因素;然而,中国的流行病学改善的影响更大.
- 由于高BMI,药物使用和高空腹血葡萄糖 (FPG) 的负担在两个地区都有所增加.
结论:
- 尽管年龄标准化率下降,但在中国和G20国家,肝癌的绝对负担上升.
- 与高BMI,药物使用和高FPG相关的发病率和负担增加,强调需要加强查和风险因素管理.
更多相关视频
09:03Establishment of Hepatocarcinoma in BALB/c-nu Mice and Investigation of the Therapeutic Effect of the Sanleng Jiashen Formula
Published on: January 26, 2024
664
07:50Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
862
相关概念视频
Diseases of the Liver and Gallbladder
1.8K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.8K
Targeted Cancer Therapies
8.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
8.6K
Cancer Survival Analysis
645
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
645
