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Updated: Jan 14, 2026

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies
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口腔潜在前恶性疾病中Y染色体的丧失预测恶性进展:一种综合性跨物种多队列生物信息学研究

Rui Han1, Jos B Poell2,3, Cristina Conde-Lopez4

  • 1Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Head & neck
|October 22, 2025
PubMed
概括

在口腔潜在恶性疾病 (OPMDs) 中发现了Y染色体 (LOY) 和Y染色体基因表达 (EDY) 的损失. 这些变化促进恶性进展,建议LOY/EDY作为诊断生物标志物和口腔状细胞癌 (OSCC) 的治疗标.

关键词:
极端下调的Y染色体基因表达 (EDY).Y染色体 (LOY) 的损失氨酸脱甲基酶5D (KDM5D) 是一种口腔潜在的先发性疾病 (OPMD)口腔状细胞癌 (OSCC) 是一种

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