GTDB第10版:对715 230种细菌和17 245种考古基因组进行完整和系统的分类
Donovan H Parks1,2, Pierre-Alain Chaumeil1,2, Aaron J Mussig1
1Australian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, The University of Queensland, Aalborg University, Brisbane, Queensland 4072, Australia.
Nucleic acids research
|October 22, 2025
概括
基因组分类数据库 (GTDB) 现在包括超过73.2万个基因组,揭示了发现主要 prokaryotic 血统的和. 然而,物种层面的发现仍在继续,其中大多数尚未被基因组表征.
科学领域:
- 微生物学 微生物学
- 生物信息学是一种生物信息学.
- 基因组学就是基因组学.
背景情况:
- 基因组分类数据库 (GTDB) 为 prokaryotic 基因组提供了一个标准化,基因组学上一致的分类学.
- 它对于组织和理解微生物生命的巨大多样性至关重要.
研究的目的:
- 介绍GTDB第10版 (R10-RS226) 的更新和改进.
- 突出方法的进步,政策的变化,以及新的用户应用.
- 概述未来的计划,包括真菌分类学和病原体分类.
主要方法:
- 使用来自NCBI大会数据库的基因组.
- 应用植物遗传学方法来进行等级规范化和物种聚类.
- 开发网站增强和面向用户的工具.
主要成果:
- GTDB R10-RS226包括715230个细菌和17245个考古基因组.
- 组织成136,646种细菌和6,968种考古物种集群.
- 表明在发现主要的 prokaryotic 分支方面已经和,而物种的发现仍在继续.
结论:
- GTDB是 prokaryotic 分类学的一个重要资源,不断更新新的基因组数据.
- 数据库反映了主要微生物多样性发现的接近和.
- 未来的工作将扩展GTDB包括真菌和增强病原体分类.
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