在废水和鸟蛋中对PFOS的异构体特定分析,通过循环离子运动谱法实现
Jenise Z Paddayuman1, Mindula K Wijayahena1, John Michael N Aguilar1
1Department of Chemistry, University at Buffalo - The State University of New York, Buffalo, New York 14260, United States.
Journal of the American Society for Mass Spectrometry
|October 22, 2025
概括
这项研究开发了一种方法来分离高甲硫酸 (PFOS) 异构体. 分支的PFOS异构体在废水中普遍存在,而线性PFOS异构体在鸟中积累.
科学领域:
- 环境化学环境化学
- 分析化学 分析化学
- 毒理学 毒理学 毒理学
背景情况:
- perfluorooctanesulfonic 酸 (PFOS) 是一个广泛存在的环境污染物.
- PFOS存在于线性 (L-PFOS) 和分支 (Br-PFOS) 异构体.
- 目前的分析经常报告了总的PFOS,忽视了同位素分布.
研究的目的:
- 开发和验证一种用于分离和量化单个PFOS异构体的方法.
- 为了研究PFOS在环境和生物样本中的异构体分布.
- 为了强调对异构体特定分析对于准确的PFOS评估的重要性.
主要方法:
- 使用超高性能液态色谱与循环离子移动性光谱学-四极飞行时间质谱学 (UHPLC-cIMS-qToF-MS) 相结合.
- 在cIMS中使用可调节的漂移长度用于基于漂移时间 (DT) 和碰撞横截面 (CCS) 的异构体分离.
- 从五个Br-PFOS异构体中分离出L-PFOS,尽管异构体没有被分解.
主要成果:
- 在MS中,分支的PFOS异构体显示出比L-PFOS更高的电离效率 (2-5倍).
- 废水样本中Br-PFOS异构体占主导地位 (>50%的PFOS总量).
- 在鸟类蛋黄样本中,L-PFOS被显著丰富 (>88%).
结论:
- 在复杂矩阵中,UHPLC-cIMS-qToF-MS有效分离和量化PFOS异构体.
- 对异构体的特定分析对于准确的PFOS量化至关重要.
- 评估PFOS异构体分布对于了解PFAS的环境命运和生物积累很重要.
关键词:
碰撞的横截面截面是什么双顶鱼是双顶鱼的一种类型.漂移时间漂移时间电离效率是电离的效率.异构体分离异构体的分离通过和多醇基物质 (PFAS)perfluorooctanesulfonic 酸 (PFOS) 的含量是什么更多相关视频
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