基于人工智能的身体成分得分预测了肝移植后的生存率
Eugen Malamutmann1, Friederike Roehrborn1, Ksenia Vershinina1
1Department of General, Visceral and Transplantation Surgery, University Medicine Essen, Hufelandstraße 55, Essen, 45147, Germany.
Langenbeck's archives of surgery
|October 22, 2025
概括
身体成分显著影响肝移植存活率. 内脏脂肪与肌肉体积的比率是男性和女性患者的关键预测指标,使用基于AI的分析来确定.
科学领域:
- 移植研究 移植研究
- 医学成像分析分析 医学成像分析
- 身体构成研究研究的研究.
背景情况:
- 身体组成是预测患有恶性疾病的患者预后的关键因素.
- 了解身体成分在肝移植中的作用对于改善患者生存率至关重要.
研究的目的:
- 评估肝移植后身体构成对短期和长期生存的预测价值.
- 调查身体组成对肝移植结果影响的性别差异.
主要方法:
- 对346名肝移植患者 (2011-2023) 进行了回顾性分析,这些患者接受了移植前的CT扫描.
- 基于人工智能的自动化评估身体组成,包括内脏和皮下脂肪和肌肉体积.
- 单变量和多变量回归分析,对男性和女性队列进行单独分析.
主要成果:
- 内脏脂肪体积与肌肉体积 (FVM-ratio) 的比率和皮下脂肪体积与肌肉体积的比率被确定为总生存时间的显著预后参数.
- 发现这些身体成分比率能够预测男性和女性患者的生存率.
- 与女性相比,男性患者的内脏脂肪和FVM比率显著更高.
结论:
- 内脏脂肪体积与肌肉体积比率 (FVM比率) 是两性肝移植后整体存活率的关键独立预测指标.
- 完全自动化的,基于人工智能的身体组成评估提供了一个快速,准确和独立于调查者的预测方法.
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