喘和慢性阻塞性肺病与发展便失禁的风险增加有关
Aditya Ashok1, Raphaëlle Varraso2, Keming Yang3,4
1Division of Gastroenterology, Weill Cornell Medical Center, New York, NY, USA.
喘和慢性阻塞性肺病 (COPD) 增加了便失禁 (FI) 的风险. 患有这些肺部疾病的女性患FI的可能性更高,突出显示了显著的关联.
科学领域:
- 肺部医学 肺部医学
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 便失禁 (FI) 是一种普遍的疾病,特别是在老年人群中.
- 阻塞性肺部疾病,如喘和慢性阻塞性肺部疾病 (COPD),与尿失禁和腹内压力升高有关.
研究的目的:
- 调查阻塞性肺部疾病 (喘,慢性肺炎) 与发展便失禁 (FI) 的风险之间的潜在关联.
主要方法:
- 使用来自护士健康研究 (NHS) 队列的数据进行了前性研究.
- 事件FI被定义为在四年后续期间 (2008-2012) 每月发生一次或多个事件.
- 考克斯的比例危险模型被用来评估FI与喘和COPD相关的风险,并对相关的共变量进行调整.
主要成果:
- 与没有喘的女性相比,喘妇女的FI风险增加了1.18倍 (aHR:1.18,95%CI:1.09-1.27).
- 与没有COPD的女性相比,患有COPD的女性患FI的风险增加了1.16倍 (aHR:1.16,95%CI:1.05-1.27).
- 患有喘/COPD重叠的女性患FI的风险最高,风险增加1.28倍 (aHR:1.28,95% CI:1.16-1.42).
结论:
- 喘和COPD与患便失禁的风险增加显著相关.
- 关联这些呼吸道疾病与FI的潜在病理生理学需要进一步研究.
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