致死性死性带炎在一只狗中是由NDM产生广泛耐药的Acinetobacter baumannii引起的:一个病例报告
Ricardo Antonio Pilegi Sfaciotte1,2, Felipe Carniel3, Leandro Parussolo4
1CEDIMA, Centro de Diagnóstico Microbiológico Animal, Department of Veterinary Medicine, Santa Catarina State University, Lages, Santa Catarina, Brazil. ricardo.sfaciotte@unesp.br.
概括
一只狗中致命的死性带炎病例是由产生新德里金属β-乳糖酶 (NDM) 的广泛耐药的Acinetobacter baumannii引起的. 这突显了物抗菌素耐药性的动物传染风险.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 死性粘膜炎是一种严重的细菌感染.
- 宝曼尼菌 (Acinetobacter baumannii) 是一种机会性病原体.
- 抗菌素耐药性是一个日益严重的全球健康问题.
研究的目的:
- 报告一只由多药性耐药性Acinetobacter baumannii菌株引起的狗中致命的死性带炎病例.
- 为了描述隔离物的抗微生物耐药性概况.
- 强调这种感染对伴侣动物的潜在动物传染性影响.
主要方法:
- 病例报告和临床观察.
- 细菌的隔离和鉴定.
- 抗菌敏感性测试,包括新德里金属β-乳酸酶 (NDM) 的表型和基因型检测.
主要成果:
- 一只狗出现了快速发病的死性带炎和败血症.
- 病原体被确定为产生NDM的Acinetobacter baumannii.
- 该分离物具有广泛的耐药性,仅对胆固醇素和B型多胺素敏感.
- 尽管进行了密集的支持性护理,但这只狗因感染而死亡.
结论:
- 这是巴西首次报告的与产生NDM的Acinetobacter baumannii相关的犬类死性带炎病例.
- 这一案例凸显了伴侣动物对广泛耐药细菌的动物传播潜力.
- 强调对兽医中抗菌素耐药性的监测和控制至关重要.
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