在帕金森病患者的步行启动过程中预先进行姿势调整:系统性审查
Mustafacan Salamci1, Arzu Guclu-Gunduz2
1Department of Neurological Physiotherapy and Rehabilitation, Gazi University, Emek, Bishkek St. No:2 Çankaya/ANKARA, Ankara, Turkey. mustafacan_341@hotmail.com.
Acta neurologica Belgica
|October 22, 2025
概括
患有帕金森病的人在步行启动 (GI) 期间表现出改变的预期性姿势调整 (APA),表现出较慢的运动和延迟的肌肉激活. 这些变化与疾病的严重程度有关,可能有助于评估跌倒风险并指导康复.
科学领域:
- 神经学 神经学
- 生物力学 生物力学
- 运动科学 运动科学
背景情况:
- 预期的姿势调整 (APAs) 对于稳定的步行启动 (GI) 是至关重要的.
- 帕金森病 (PD) 具有影响平衡和运动的运动缺陷的特征.
- 了解PD中的APA变化对于临床评估和康复至关重要.
研究的目的:
- 在患有帕金森病 (pwPD) 的人群中,审查胃肠道期间APAs的变化.
- 探索 pwPD 中的 APA 措施的临床适用性.
主要方法:
- 在PubMed和Web of Science进行系统的文献搜索.
- 为APAs提取压力中心 (CoP) 和电肌图 (EMG) 的数据.
- 使用纽卡斯尔-太华尺度进行质量评估.
主要成果:
- 审查了14项研究,涉及453名 pwPD和287名健康受试者 (HS).
- pwPD显示较小,较慢的COP位移和延长的APA持续时间.
- 电磁共振显现了关键肌肉的延迟发病和降低幅度,与疾病严重程度和步态结 (FoG) 有关.
结论:
- 在胃肠道过程中,pwPD表现出布拉迪动力学和低动力学APAs.
- 基于GI的APA措施可以帮助评估姿势稳定性,步态和跌倒风险.
- 需要标准化的GI协议来临床翻译APA测量.
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