喉癌负担的流行病学趋势:来自GBD 2021和SEER数据库的见解
Jie Zhang1, Shuixiu Yu2, Feng Wang1
1Department of Radiotherapy, Jingjiang People's Hospital Affiliated to Yangzhou University, No.28 Zhongzhou Road, Jingjiang, 214500, Jiangsu, China.
Discover oncology
|October 22, 2025
概括
从1990年到2021年,全球喉癌 (LC) 发病率和死亡率下降,男性不成比例地受到影响. 高收入国家和低收入国家之间的健康差异扩大,需要有针对性的公共卫生战略.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 癌症研究 癌症研究
背景情况:
- 喉癌 (LC) 构成了全球重大健康负担.
- 了解当前的趋势和状态对于有效的公共卫生干预至关重要.
研究的目的:
- 分析喉癌发病率,死亡率和残疾调整寿命年 (DALYs) 的全球,区域和国家趋势.
- 调查LC负担的驱动因素,包括人口动态和流行病学变化.
- 量化跨国LC负担的不平等,并评估美国的趋势.
主要方法:
- 用于全球和区域分析的2021年全球疾病负担 (GBD) 数据.
- 使用分解分析来确定LC负担的驱动因素.
- 使用世卫组织标准的健康公平方法量化健康不平等.
- 分析了使用SEER数据和发病率和死亡率 (AAPC) 结点回归的美国趋势.
主要成果:
- 全球LC发病率和死亡率在1990年至2021年期间下降,男性的负担更高.
- 人口增长是LC负担的主要驱动因素,区域和性别差异不同.
- 根据残疾调整的寿命年 (DALYs) 在低收入国家更高,差距越来越大.
- 美国LC发病率下降 (1992-2021年),而基于发病率的死亡率 (IBM) 增加到2003年,然后下降.
结论:
- 从1990年到2021年,全球喉癌的患病率有所下降,但男性仍然不成比例地受到影响.
- 在社会人口指数 (SDI) 较高和较低的国家之间,LC负担的差距越来越大.
- 有针对性的公共卫生战略对于解决喉癌的流行病学趋势和社会人口学不平等至关重要.
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