使用巨孔树脂从沙法兰花中丰富甲-3-O-Sophoroside:静态吸附特性和动态优化基于分析层次的过程-度重量方法-响应表面方法
Xinyi Huo1, Liling Wang2, Lele Li1
1School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China.
Journal of separation science
|October 22, 2025
概括
这项研究优化了使用XAD-1600N树脂从撒弗朗中获得kaempferol-3-O-sophoroside的丰富. 开发的方法显著增加了纯度,支持大规模的自然产品利用.
科学领域:
- 自然产品化学 自然产品化学
- 分离科学 分离科学
- 生物化学工程 生物化学工程
背景情况:
- 沙弗朗花是丰富的生物活性化合物的来源,如kaempferol-3-O-sophoroside.
- 有效的提取和净化方法对于利用这些化合物至关重要.
研究的目的:
- 开发一种有效的策略,从番茄花叶提取物中丰富卡姆费罗-3-O-sophoroside.
- 使用多标准决策方法优化动态丰富参数.
主要方法:
- 用于吸附/脱附的宏树脂 (XAD-1600N) 的选择和表征.
- 调查静态吸附等热体 (伪二次,弗洛伊德利希,兰格穆尔) 和热力学分析.
- 使用动态丰富的优化 分析层次 过程-重量方法-响应表面方法.
主要成果:
- 在XAD-1600N树脂中,Kempferol-3-O-sophoroside具有很高的吸附和脱附能力.
- 吸附遵循伪二阶,弗洛伊德利希和兰格穆尔模型,表明自发的外热过程.
- 优化的参数产生了 >5倍的纯度增加,可接受的回收.
结论:
- 开发的丰富策略是有效的净化卡姆费罗-3-O-sophoroside从沙夫兰.
- 这项研究为大规模开发和应用kaempferol-3-O-sophoroside提供了理论基础.
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