慢性胃肠道疾病在患有口唇裂和/或口腔裂的患者中的患病率
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Updated: Jan 6, 2026
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Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
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Eliane Alves Motta Cabello Santos1, Eloá Cristina Passucci Ambrosio2, Thais Marchini Oliveira3
1Department of Pediatrics, Bauru School of Medicine and Hospital for the Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, São Paulo, Brazil.
概括
患有唇和/或裂 (CL/P) 的儿童和青少年患慢性腹痛 (CAP) 的比率更高. 虽然功能性便秘 (FC) 在这两组中都是常见的,但CAP对CL/P患者产生了重大影响,突出了综合护理的需要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 头骨面部异常 头骨面部异常
- 慢性疼痛综合征 慢性疼痛综合征
背景情况:
- 唇裂和/或裂 (CL/P) 是一种常见的先天性疾病.
- 患有CL/P的儿童可能面临独特的挑战,包括潜在的胃肠道问题.
- 慢性腹痛 (CAP) 和功能性便秘 (FC) 是儿童群体中普遍存在的功能性胃肠道疾病.
研究的目的:
- 为了比较慢性腹痛 (CAP) 和功能性便秘 (FC) 在有或没有裂口和/或 palates (CL/P) 的儿童和青少年的患病率.
- 为了研究一个假设,口腔裂的个体表现出更高的患病率这些慢性胃肠道疾病由于早期生活压力因素.
主要方法:
- 这是一项回顾性横截面研究,涉及400名年龄在4-18岁的参与者.
- 参与者被分为两组:非综合征性CL/P (n=200) 和没有CL/P (n=200) 的对照组.
- 家长的采访和问卷使用了APley和Naish标准来诊断CAP和ROME IV标准来诊断FC,使用奇平方测试来比较患病率.
主要成果:
- 与对照组 (15.00%) 相比,在CL/P组中,CAP的患病率明显高 (36.50%) (P < .001).
- 在CL/P组中,FC的患病率为24.50%,在对照组中为18.50%,没有统计学上显著的差异 (P = .180).
- 功能性便秘在两组中都显著存在,这表明了一般的易感性.
结论:
- 与没有CL/P的同龄人相比,患有CL/P的儿童和青少年患有慢性腹痛的患病率明显高.
- 胃肠道问题,特别是CAP,可能会导致裂患者的额外痛苦.
- 慢性胃肠道疾病的综合管理应成为儿童CL/P患者综合康复的组成部分.
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