巴西带有症状的外周动脉疾病患者的死亡率:性别比较
Breno Quintella Farah1, Raphael Mendes Ritti-Dias2, Raquel Santana Fernandes2
1Universidade Federal Rural de Pernambuco, Recife, PE, Brazil.
Einstein (Sao Paulo, Brazil)
|October 22, 2025
概括
与女性相比,患有间歇性关的男性死亡风险更高. 这项研究强调,需要进行性别特定的研究,以减少这一患者群的死亡率,特别是在低收入和中等收入国家.
科学领域:
- 心血管医学 心血管医学
- 流行病学 流行病学
- 老年学是一门学科.
背景情况:
- 间歇性,是外周动脉疾病的症状,影响患者的流动性和生活质量.
- 心血管疾病结果的性别差异已经得到了充分证实,但间歇性关队列中的特定死亡风险需要进一步调查.
研究的目的:
- 为了比较巴西大都会队列中被诊断患有间歇性关节障碍的男性和女性之间的全因死亡率.
- 为了确定与增加死亡风险相关的因素在这个人群中.
主要方法:
- 一组215名间歇性听患者 (65.3%是男性,平均年龄67岁) 平均被跟踪了5.2年.
- 收集的数据包括社会人口统计,并发症和六分钟步行测试结果. 使用考克斯回归分析来确定死亡风险.
- 死亡被系统地记录下来,并记录了原因,心血管疾病是主要原因.
主要成果:
- 在随访期间,共有105名患者 (58.9%为男性) 死亡. 已故的患者年龄较大,高血压较高,步行距离较短.
- 与女性相比,男性的全因死亡风险明显更高 (HR: 2.774; 95%CI: 1.316-5.847).
- 这种男性的风险增加在调整年龄,COPD,六分钟步行距离和脚-手腕指数后仍然存在.
结论:
- 与女性相比,患有间歇性关的男性面临的全因死亡风险要大得多.
- 进一步的研究至关重要,以揭示这一群体中特定于性别的死亡风险因素.
- 研究结果可以为有针对性的干预措施提供信息,以减少死亡率,特别是在资源有限的环境中,对有间歇性关节障碍的男性来说.
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