慢性阻塞性肺部疾病患者体育活动,久坐行为和日常症状之间的双向关联:纵向观察性研究
Banchia Palmen1,2, Zjala Ebadi3,4, Maarten van Herck2
1Institute of Nutrition and Translational Research in Metabolism, Care and Public Health Research Institute, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
JMIR mHealth and uHealth
|October 22, 2025
概括
身体活动 (PA) 和久坐时间 (ST) 与慢性阻塞性肺病 (COPD) 患者的症状有双向关联. 增加的PA与感觉放松有关,而更高的步数和ST与呼吸短促,疲劳和焦虑相关.
科学领域:
- 肺部医学 肺部医学
- 行为医学是一种行为医学.
- 生物医学工程 生物医学工程
背景情况:
- 在慢性阻塞性肺病 (COPD) 患者中,基于问卷的症状评估受到回忆偏差的限制,缺乏双向探索.
- 身体活动 (PA),久坐时间 (ST) 和COPD患者的症状体验之间的关系尚不清楚.
- 了解这些关联对于开发有效的症状管理策略和改善患者生活质量至关重要.
研究的目的:
- 为了调查PA,ST和COPD患者的症状之间的关联的方向性.
- 利用加速计和生态瞬间评估 (EMA) 等客观措施进行实时数据收集.
- 提供关于COPD行为和症状感知之间的复杂相互作用的见解.
主要方法:
- 来自FAntasTIGUE研究的COPD患者的一个子样本参与了这项研究,每天填写8个EMA问卷,持续5天.
- 通过7点利克尔特尺度评估了10种症状,并通过加速计测量客观测量了步数和ST (ActiGraph GT9X链接).
- 多级模型分析了PA/ST (15分钟和30分钟前/后EMA) 和症状得分之间的关系,控制共变量并使用患者ID作为随机拦截.
主要成果:
- 更放松的感觉与EMA后15分钟更高的步数相关 (P=.046).
- 相反,更高的预EMA步数与感觉不那么放松 (P=.02,P=.009),呼吸短促 (P<.001) 和疲劳 (P=.02) 的增加有关.
- 升高的前EMAST与增加的焦虑相关 (P=.03,P=.04).
结论:
- 在COPD患者中,感觉放松和PA之间存在双向关系.
- 增加的体力活动 (更高的步数) 与更大的呼吸短促和疲劳有关.
- 较长的久坐时间与增加的焦虑感有关.
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