当地环境特征和2型糖尿病:绿色设施,可行性指标和空气污染与发病率有关
David S Curtis1, Huong D Meeks2, Ken R Smith1
1Department of Family & Consumer Studies, University of Utah, Salt Lake City, UT 84112, USA.
Environment international
|October 22, 2025
概括
生活在更绿色的地区和促进活跃的通勤可能会降低2型糖尿病 (T2D) 的风险. 相反,较高的空气污染和城市密度与T2D发病率的增加有关. 环境因素显著影响代谢健康.
科学领域:
- 环境流行病学环境流行病学
- 公共卫生 公共卫生
- 城市规划是城市规划.
背景情况:
- 2型糖尿病 (T2D) 发病率受到各种环境因素的影响,但对共暴露和混因素的纵向数据计算有限.
- 了解这些关联对于开发有效的公共卫生干预和城市规划策略至关重要.
研究的目的:
- 估计各种环境属性与T2D发病率之间的纵向关联.
- 调查绿色设施,空气污染,可行性和食品零售商的可用性对T2D风险的独立影响,同时控制混变量.
主要方法:
- 利用犹他州人口数据库对1970年至1990年间出生的大量队列 (N=909,729) 进行了分析.
- 客观测量时间变化的环境属性和相关的T2D诊断从1996-2019年.
- 采用了考克斯回归模型,调整个人和区域级社会经济因素,地理相关性和T2D家族史.
主要成果:
- 增加的住宅绿化 (区块组级) 和绿地覆盖与降低T2D危险 (HR=0.945,HR=0.984) 相关.
- 较高的活跃通勤率 (HR=0.964) 与较低的T2D风险有关,而较高的环境颗粒物 (HR=1.079) 和交叉点密度 (HR=1.026) 与T2D风险增加有关.
- 人口密度和食品零售商的可用性没有与T2D危险有显著的关联.
结论:
- 绿色设施和积极的通勤是防止T2D发病率的保护因素.
- 空气污染和某些城市土地使用模式 (交叉密度) 是T2D的风险因素.
- 绿色空间和空气质量等环境属性是人口层面代谢健康战略的重要考虑因素.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
4.3K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.3K
Diabetes: Symptoms, Diagnosis, and Complications
2.0K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.0K
Pathophysiology of Diabetes
3.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.1K
Diabetes Mellitus: Overview and Type I Subtype
4.9K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.9K
Coronary Artery Disease I: Introduction
876
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
876
Psychoneuroimmunology: Diabetes and Cancer
437
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
437


