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软组织治愈的分析,用血小板丰富的纤维素膜密封的插座孔

Rann Manlerd¹, Bundhit Jirajariyavej¹, Nisarat Ruangsawasdi²

¹Faculty of Dentistry, Mahidol University, Bangkok, Thailand.

European journal of dentistry

|October 22, 2025

概括

与原体和富含血小板纤维素的纤维素 (L-PRF) 相比,与原体海绵或没有治疗相比,改善了软组织愈合和减少了拔牙后的疼痛. 然而,L-PRF并没有增强伤口关闭,这表明对提取后再生的长期益处有限.

科学领域:

口腔外科手术和再生医学
牙科中的生物材料.
伤口愈合研究研究研究

背景情况:

插座密封有助于提取后保持膜脊.
白细胞和血小板丰富的纤维素 (L-PRF) 是一种促进愈合的自身物质.
对软组织愈合与原体海绵或自发愈合的L-PRF的比较数据有限.

研究的目的:

用L-PRF膜,原体海绵或自发愈合来评估牙提取后软组织愈合结果.
为了在治疗组中比较伤口边缘距离,炎症,术后疼痛和伤口关闭区域.

主要方法:

一个随机控制的临床试验,涉及45个提取地点.
插座被随机分为L-PRF密封,原体海绵密封或自发愈合.
主要结果:伤口边缘减少,软组织愈合指数,疼痛;次要结果:伤口关闭区域.

主要成果:

与原体海绵和自发愈合相比,L-PRF在第7天显示出明显优异的软组织愈合指数.
在第五天,L-PRF比原体海绵和自发愈合更能减少术后疼痛.
两组之间在伤口关闭或面积减少方面没有发现显著差异.

结论:

在提取后的第一周内,L-PRF增强了早期软组织愈合,并减少了手术后的疼痛.
与原体海绵或自发愈合相比,L-PRF在伤口关闭方面没有提供额外的好处.
虽然L-PRF可以提供短期的症状缓解,但它并不能显著改善提取后的软组织再生在临床上相关的水平.

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