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Updated: Jan 6, 2026

Combined Conditional Knockdown and Adapted Sphere Formation Assay to Study a Stemness-Associated Gene of Patient-derived Gastric Cancer Stem Cells
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Combined Conditional Knockdown and Adapted Sphere Formation Assay to Study a Stemness-Associated Gene of Patient-derived Gastric Cancer Stem Cells

Published on: May 9, 2020

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形DNA结构激活cGAS-STING通路,用于增强结直肠癌检查点免疫治疗

Yu Zhang1, Li He2, Shixu Kou2

  • 1Department of Oncology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, 214122, PR China; Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu Province, 214122, PR China.

International journal of biological macromolecules
|October 22, 2025
PubMed
概括

研究人员开发了一种新的DNA结构,可以精确地激活干扰素基因 (STING) 途径的循环GMP-AMP合成酶 (cGAS) 刺激器. 这种方法通过克服瘤耐药性,提高了结直肠癌 (CRC) 免疫治疗的有效性.

关键词:
亚普特美尔 (Aptamer) 是一种药物.结肠直肠癌是什么意思免疫治疗是一种免疫疗法.cGAS-STING 的使用情况.

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