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由伪造的血糖类产品引起的低血糖昏迷:一个案例报告
Giulia Antonacci1, Erika Bortignon1, Massimo Bolognesi1
1Department of Medicine, University of Padova, Padua, Italy.
European journal of hospital pharmacy : science and practice
|October 22, 2025
概括
在网上销售的伪造的半谷氨酸 (Ozempic) 含有胰岛素,导致患者陷入低血糖昏迷. 这凸显了不受监管的在线药品市场的危险性以及需要采取监管行动的必要性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 赛马格卢提德 (Ozempic,Rybelsus,Wegovy),一种GLP-1受体激动剂,广泛用于2型糖尿病和体重控制.
- 它在减肥方面的受欢迎程度急剧上升,导致非标签使用的增加和对塞马格卢提德的高需求.
- 这种需求推动了来自不受监管的在线来源的伪造的西马格卢提德产品的激增.
研究的目的:
- 报告与在线获得的伪造的塞马格卢提德自给药相关的严重不良事件.
- 要强调与在线药品市场上可获得的假冒药物相关的风险.
- 倡导加强监管措施,以防止未来的事件.
主要方法:
- 一个临床病例的介绍,涉及一个31岁的女性.
- 由于在自行服用一种产品后出现低血糖昏迷的急诊室入院,该产品据称是塞马格卢提德 (Ozempic).
- 用药瓶的毒理分析.
主要成果:
- 通过在线网站获取的瓶子被发现含有胰岛素而不是黄胺.
- 患者经历了严重的低血糖症,作为注射胰岛素的直接后果.
- 这一事件表明,在线药物供应链中出现了严重的故障.
结论:
- 伪造的药物,比如在这种情况下伪装成黄胺的胰岛素,对健康构成重大风险.
- 不受监管的在线药品市场对患者安全的担忧越来越大.
- 紧急监管干预是必要的,以打击假冒药品的销售和减轻严重的不良事件.
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