单个中心的经验,覆盖的支架关闭的阴道静脉心房隔膜缺陷
Ata Firuzi1, Zahra Khajali2, Sedigheh Saedi2
1Cardiovascular intervention research center, Rajaie cardiovascular medical and research institute, Tehran, 1995614331, Iran.
Scientific reports
|October 22, 2025
概括
使用覆盖式支架关闭阴道静脉心脏隔膜缺陷 (SVASD) 的跨导管关闭是可行的和安全的. 这种微创手术技术有效地减少了患者的转向和改善了心脏功能,为手术提供了可行的替代方案.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 阴道静脉心房隔膜缺陷 (SVASD) 是一种复杂的先天性心脏异常.
- 手术修复传统上涉及显著的侵入性.
- 穿皮关闭提供了一个不那么侵入性的替代方案,但对SVASD仍然存在挑战.
研究的目的:
- 评估对SVASD进行透导管关闭的可行性,安全性和短期结果.
- 评估使用覆盖式支架在皮肤间的SVASD修复中的有效性.
- 为了确定对血液动力学参数和心脏功能的影响.
主要方法:
- 追溯分析24名患者 (15-70岁) 的高级SVASD和显著的左至右转移 (QP/QS≥1.5).
- 在2021年6月至2023年12月期间使用覆盖式支架进行皮肤封闭.
- 使用了手术前后成像 (TEE,CTA,TTE) 和血液动力学评估.
主要成果:
- 技术成功率为96%,其中一个装置的栓塞需要手术.
- 中位数QP/QS比率显著下降,从1.8降至1.1 (p < 0.001).
- 在3个月后,右心室功能障碍 (p=0.004) 和扩大 (p=0.001) 显著改善.
结论:
- 用覆盖的支架封闭SVASD的跨导管封闭是可行的,安全和有效的.
- 这种最少的侵入性方法显示出积极的短期结果和功能改善.
- 覆盖式支架修复为适合的SVASD患者提供了一种有希望的外科手术替代方案.
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