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阿穆尔鱼 (Rhynchocypris lagowskii) 的染色体层次的基因组组合

Xiaohui Bai¹, Hanlin Li¹, Yaoxin Wang¹

¹Tianjin Fisheries Research Institute, Tianjin, 300221, China.

Scientific data

|October 22, 2025

概括

研究人员生成了第一个染色体水平的基因组组合,用于阿穆尔鱼 (Rhynchocypris lagowskii),这是一个重要的淡水鱼. 这种高质量的基因组资源将有助于未来对鱼类遗传学和养殖的研究.

科学领域:

基因组学就是基因组学.
水生生物学水生生物学
渔业科学渔业科学

背景情况:

阿穆尔小鱼 (Rhynchocypris lagowskii) 是一种在中国河流系统中发现的具有经济意义的淡水鱼.
之前没有报告R. lagowskii的基因组数据,这限制了遗传和育种研究.

研究的目的:

为阿穆尔鱼 (Rhynchocypris lagowskii) 构建第一个染色体级基因组组.
为未来对这一重要鱼类物种的研究提供高质量的基因组资源.

主要方法:

整合了MGI,PacBio HiFi和Hi-C测序技术.
染色体层次的基因组组装和基因预测.
使用脚手架N50和BUSCO分数进行质量评估.

主要成果:

通过32.63 Mb的N50脚手架实现了1,041.22 Mb的基因组组装.
99.04%的基因组序列被定在25个染色体上.
预测了32425个编码蛋白质的基因,具有91.09%的功能注释和高BUSCO得分 (96.32%的组装,97.53%的注释).

结论:

一个高质量的,染色体水平的基因组组合R. lagowskii成功构建.
这种基因组作为比较基因组学,种群遗传学和阿穆尔小鱼分子繁殖的基础资源.
促进了这个经济上有价值的鱼类的功能性勘探和保护工作.

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