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Updated: Jan 14, 2026

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
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关于CAR T细胞在自身免疫性疾病中的潜力

Johanna Richter1, Martin Krusche2, Isabell Haase2

  • 1Department for Stem Cell Transplantation, University Medical Center Hamburg, Hamburg, Germany.

Immunotherapy
|October 23, 2025
PubMed
概括

化学抗原受体 (CAR) T细胞疗法对自身免疫性疾病具有前景,比目前的治疗方法提供更深层次的B细胞枯竭. 早期研究表明耐受性良好,并且在耐火病例中有令人鼓舞的反应.

关键词:
在CAR T细胞疗法中.化学抗原受体T细胞的T细胞.自身免疫性疾病 自身免疫性疾病自主反应的B细胞.细胞治疗疗法细胞治疗疗法

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