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对避免事件比率的样本大小估计

David T Dunn1, Oliver T Stirrup2, David V Glidden3

  • 1MRC Clinical Trials Unit, University College London, London, UK.

Clinical trials (London, England)
|October 23, 2025
PubMed
概括

避免事件比率 (AER) 提供了一种更易于解释和更有效的方式来设计非劣势试验. 使用AER可以显著减少样本大小要求,使研究更具成本效益.

关键词:
95-95方法的使用.积极控制试验的试验.避免了事件的发生.估计和估计和估计.没有劣等的非劣等性.效果的维护 - 效果的维护样本的大小 样本大小

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