对罕见的ABh变异血型的产前临床管理
Aritri Mandal1, Laura Eastwood2, Shane Grimsley3
1Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Transfusion medicine (Oxford, England)
|October 23, 2025
概括
管理罕见血型如ABh的怀孕需要仔细规划. 这个案例表明,一个拥有抗H,抗A和抗B抗体的女性成功进行了无输血分娩.
科学领域:
- 免疫血液学 免疫血液学
- 产科 产科 产科 产科 产科
- 输血医学 输血医学
背景情况:
- H抗原是A和B血型的前体,H阴性个体在英国很少见.
- 该案涉及一名怀孕妇女,她患有极为罕见的ABh表型和对H,A和B抗原的抗体.
研究的目的:
- 描述患有罕见血型和多个抗体的患者高风险怀孕的管理.
- 突出多学科团队 (MDT) 协作和精心规划在管理此类案件的重要性.
主要方法:
- 一个多学科的团队制定了一个全面的出生管理计划,包括一个新的阴道细胞救援政策.
- 兼容性测试发现只有H- (OH) 和ABh红细胞适合输血.
主要成果:
- 患者在不需要输血的情况下成功通过阴道分娩.
- 在MDT的详细规划确保了一个安全的结果,尽管缺乏兼容的血液单位.
结论:
- 对罕见血型孕妇的最佳护理需要广泛的规划和合作.
- 管理原则适用于其他情况下,输血是禁忌或拒绝的.
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