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肠道微生物群和高血压风险的饮食指数:一个横截面NHANES研究
Xiaona Che1, Xinqi Li1, Lin Na1
1Department of Cardiology, The Second Hospital of Jilin University, Changchun, China.
与肠道微生物群相关的饮食指数,特别是DI-GM和BGMS,显示与高血压患病率有显著的反向关联. BGMS显示出对高血压的更强的保护作用.
科学领域:
- 营养科学 营养科学
- 微生物学 微生物学
- 心血管健康 心血管健康
背景情况:
- 新出现的证据表明肠道微生物群和高血压之间存在联系.
- 对微生物群相关的饮食指数 (DI-GM,BGMS,UGMS) 的系统研究是有限的.
研究的目的:
- 调查三种与微生物群相关的饮食指数 (DI-GM,BGMS,UGMS) 与高血压患病率之间的关联.
- 通过使用大型,具有全国代表性的数据集来分析这种关系.
主要方法:
- 使用NHANES数据 (1999-2020) 对41,193名成年人的横截面研究.
- 进行了加权后勤回归,限制立方线 (RCS) 分析和子组分析.
- 研究了DI-GM,BGMS,UGMS和高血压患病率之间的关联.
主要成果:
- DI-GM和BGMS都与高血压患病率有显著和反向相关.
- 一个单位的DI-GM增加与4%的高血压风险降低相关 (OR=0.96).
- 一个单位的BGMS增加与5%的高血压风险降低相关 (OR=0.95),显示出更强的保护作用.
结论:
- DI-GM和BGMS显示与高血压患病率有显著的反向关联.
- 与DI-GM相比,BGMS表现出更强的抗高血压保护作用.
- 在UGMS和高血压患病率之间没有发现显著的关系.
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